Antibacterial Use and Level of Resistance in Poultry: A Retrospective Study in North-Central and South-West Nigeria

Kantiyok T. JOSİAH; Arowolo O.A. REUBEM; Semaka A. ASAAGA; Gberindyer F. AONDOVER

Year 2018, Volume 15 , Issue 1, Pages 13 - 17 2018-07-24

Zotero |

Mendeley |

EndNote | BibTex | Cite

PDF

en
tr
Antibacterial Use and Level of Resistance in Poultry: A Retrospective Study in North-Central and South-West Nigeria
Kanatlılarda Antibakteriyel kullanımı ve Direnç Seviyesi: Orta-Kuzey ve Güney-Batı Nijerya’da Geçmişe Yönelik Bir Çalışma

Kantiyok T. JOSİAH ^[1] , Arowolo O.A. REUBEM ^[2] , Semaka A. ASAAGA ^[3] , Gberindyer F. AONDOVER ^[4]

There is no doubt that antibacterial agents have saved the human race as well as animals from deaths and sufferings due to bacterial diseases. However, bacterial resistance is a major threat to human and animals. The objectives of this study were to investigate the pattern of antibacterial use in poultry, and the level of resistance by common bacterial agents of economic importance in Nigeria. Pattern of antibacterial use in poultry practice in North-Central and South-West Nigeria were obtained from 150 questionnaires administered to practicing veterinarians, animal health workers and poultry farmers. Again, the level of antibacterial resistance was investigated employing laboratory results from three renowned veterinary diagnostic laboratories in the country where the rates of sensitivity as well as resistance were obtained. Among the commonly used antibiotics in poultry practice, doxycycline and oxytetracycline were the most frequently prescribed for chickens infected with common bacteria organisms. Well over 50% of the treatments with different antibiotics did not follow the specifications, including dosage regimen. Over 50% of Salmonella spp, Pasteurella spp, Avibacterium paragallinarum, Mycoplasma spp, and Escherichia coli clinical isolates from poultry were resistant to the commonly used antibacterial agents such as amoxicillin, ampicillin, colistin, gentamicin, tylosin, erythromycin, and enrofloxacin. The observed inappropriate use of antibacterial agents in poultry could explain the high prevalence of bacterial resistance to common antibacterial agents. Judicious antibacterial use in poultry practice is imperative in order to circumvent the emergence of resistant bacteria organisms, public health implications, and economic losses in poultry production.

Şüphesiz antibiyotikler hayvanların yanı sıra insanları da bakteriyel hastalıklar ve bunlardan kaynaklanan ölümlerden kurtarmıştır. Ancak, bakteriyel direnç insan ve hayvanları çok ciddi tehdit etmektedir. Bu çalışmanın amacı Nijerya’da kanatlılarda antibiyotik kullanımını ve ekonomik öneme sahip yaygın antibiyotiklere karşı direnç düzeyini araştırmaktı. Orta-Kuzey ve Güney-Batı Nijerya’da kanatlı pratiğinde antibiyotik kullanım şekli veterinerler, hayvan sağlığı ile ilgili çalışanlar ve kanatlı yetiştiricilerine 150 anket uygulanarak elde edilmiştir. Yine, duyarlılık ve direnç oranlarının elde edildiği, ülkedeki üç tanınmış veteriner tanı laboratuvarından laboratuvar sonuçları kullanılarak antibakteriyel direnç düzeyi araştırılmıştır. Kanatlı pratiğinde yaygın olarak kullanılan doxycycline ve oxytetracycline yaygın bakteriyel enfeksiyonlarda en sık reçete edilen antibiyotiklerdi. Farklı antibiyotiklerle tedavilerin %50’den fazlasında antibiyotik dozu da dahil, spesifikasyonlar izlenmiyordu. Salmonella spp, Pasteurella spp, Avibacterium paragallinarum, Mycoplasma spp, ve Escherichia coli’nin kanatlılardan elde edilen klinik izolatlarının %50’den fazlası amoxicillin, ampicillin, colistin, gentamicin, tylosin, erythromycin ve enrofloxacin gibi yaygın olarak kullanılan antibiyotiklere dirençliydi. Kanatlılarda antibiyotiklerin uygunsuz kullanımı, yaygın antibiyotiklere karşı yüksek antibakteriyel direnç prevalansını açıklayabilmektedir. Kanatlı yetiştiriciliğinde dirençli bakterilerin ortaya çıkmasını, halk sağlığını etkilemesini ve ekonomik kayıpları önlemek için kanatlılarda doğru antibiyotik kullanımı zorunludur.

Antibacterial drugs, Antibacterial resistance, Poultry, Prescription pattern

Antibiyotikler, Antibiyotik direnci, Kanatlı hayvanlar, Reçete

1. McEwen, S.A. and Fedorka-Cray, P.J. 2002. Antimicrobial use and resistance in animals. Clinical Infectious Diseases, 34: 93-106.
2. WHO. 2007. Progress in the rational use of medicines. World Health Assembly Resolution. Sixtieth World Health Assembly, Document No. WHA60.16 (2007). http://apps.who.int/medicinedocs /en/d/Js21451ar/. Accessed: 20:01:2017.
3. Cizman, M. 2003. The use and resistance to antibiotics in the community. International Journal of Antimicrobial Agents, 21(4):297-307.
4. Fleming, A. 1945. Penicillin. Nobel Lecture.
5. Goossens, H. 2011. Expert-proposed European strategies to monitor and control infection, antibiotic use, and resistance in health care facilities. Lancet, 11(5):338-340.
6. Carlet, J., Collignon, P., Goldmann, D., Gyssen K. and Jarlier V et al. 2011. Society’s failure to protect a precious resource: antibiotics. Lancet, 378(9788):369-371.
7. Caprioli, A., Busani, L., Martel, J.L. and Helmuth, R. 2000. Monitoring of antibiotic resistance in bacteria of animal origin: epidemiological and microbiological methodolo¬gies. International Journal of Antimicrobial Agents, 14:291-294.
8. Aliu, Y. O. 2011. Veterinary pharmacology, 1st edition, Tamaza press, Zaria, Nigeria. 414 pp.
9. Geser, N., Stephan, R. and Hachler, H. 2012. Occurrence and characteristics of extended-spectrum Β -lactamase (ESBL) producing enterobacteriaceae in food producing animals, minced meat and raw milk. BMC Veterinary Research, 8:21. 10. vanBoeckel, T. P. 2014. Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data. The Lancet Infectious Diseases, 14(8):742–750.
11. WHO. 2014. Antimicrobial resistance global report on surveillance. http://www.who.int/drugresistance/docu. Accessed: 20:01:2017.
12. Blackall, P. J., Matsumoto, M. and Yamamoto, R. 1997. Infectious Coryza. In: Calnek, B.W., Barnes, H.J., Beard, C.W., McDougald, L.R., Saif, Y.M., Ed. Diseases of poultry. 10th edition, Iowa State University Press, USA. pp. 179-190.
13. Blackall, P.J. 1999. Infectious Coryza: overview of the disease and new diagnostic options. Clinical Microbiology Review, 12(4):627-632.
14. Moemen, A.M., Mohamed‐Wael, A.M., Ahmed, I.A., Awad, A.I. and Mohamed, S. A. 2012. Pasteurella multocida in backyard chickens in Upper Egypt: incidence with polymerase chain reaction analysis for capsule type, virulence in chicken embryos and antimicrobial resistance.Veterinaria Italiana, 48 (1):77‐86.
15. Atere, A.V., Bamikole, A.M., Oluyege, A.O., Ajurojo, O.A. and Alo, O.S. 2015. Prevalence and antibiotic resistance of Pasteurella multocida isolated from chicken in Ado-Ekiti metropolis. International Journal of Scientific World, 4 (2): 40-42.
16. Foley, S. N., Lynne, A. M. and Nayak, R. 2008. Salmonella challenges: Prevalence in swine, poultry, and potential pathogenicity of such isolates. Journal of Animal Science, 86: E149–E16.
17. Enabulele, S.A., Amune, P.O. and Aborisade, W.T. 2010. Antibiogram of Salmonella isolates from poultry farms in Ovia North Local Government Area, Edo State, Nigeria. Agriculture and Biology Journal of North America, 1(6):1287-1290.
18. Nchawa, Y.Y. and Bassey, E.B. 2015. Antimicrobial Susceptibility Patterns of Salmonella Species from Sources in Poultry Production Settings in Calabar, Cross River State, Nigeria. American Journal of Health Research, 3(2):76-81.
19. Musa, I.W., Mansur, M.S., Saidu, L., Mohamed, B. and Kaltungo, B.Y et al. 2014. Isolation and Antibiogram of Salmonella species from water and poultry feed in selected commercial farms in Zaria, Nigeria. Journal of Agriculture and Veterinary Sciences, 2(2):78-80.
20. Raji, M.A. 2014. General overview of Escherichia coli infections in animals in Nigeria. Epidemiology, 4: 2161-1165.
21. Ojo, O.E., Ogunyinka, O.G., Agbaje, M., Okuboye, J.O. and Kehinde, O.O. et al., 2012. Antibiogram of Enterobacteriaceae isolated from free-range chickens in Abeokuta, Nigeria. Veterinarski Archiv, 82(6):577-589.

Primary Language	en
Journal Section	Research Article
Authors	Author: Kantiyok T. JOSİAH (Primary Author) Country: Nigeria Author: Arowolo O.A. REUBEM Country: Nigeria Author: Semaka A. ASAAGA Country: Nigeria Author: Gberindyer F. AONDOVER Country: Nigeria
Dates	Publication Date : July 24, 2018

Bibtex	@research article { jpr447047, journal = {Journal of Poultry Research}, issn = {1302-3209}, eissn = {2147-9003}, address = {avukçuluk Araştırma Enstitüsü Müdürlüğü Şehit Cem Ersever Caddesi 9/11 Gayret Mahallesi Yenimahalle/ANKARA}, publisher = {Tavukçuluk Araştırma Enstitüsü Müdürlüğü}, year = {2018}, volume = {15}, pages = {13 - 17}, doi = {}, title = {Antibacterial Use and Level of Resistance in Poultry: A Retrospective Study in North-Central and South-West Nigeria}, key = {cite}, author = {T. Josi̇ah, Kantiyok and O.a. Reubem, Arowolo and A. Asaaga, Semaka and F. Aondover, Gberindyer} }
APA	T. Josi̇ah, K , O.a. Reubem, A , A. Asaaga, S , F. Aondover, G . (2018). Antibacterial Use and Level of Resistance in Poultry: A Retrospective Study in North-Central and South-West Nigeria . Journal of Poultry Research , 15 (1) , 13-17 . Retrieved from https://www.turkishpoultryscience.com/en/pub/issue/38531/447047
MLA	T. Josi̇ah, K , O.a. Reubem, A , A. Asaaga, S , F. Aondover, G . "Antibacterial Use and Level of Resistance in Poultry: A Retrospective Study in North-Central and South-West Nigeria" . Journal of Poultry Research 15 (2018 ): 13-17 <https://www.turkishpoultryscience.com/en/pub/issue/38531/447047>
Chicago	T. Josi̇ah, K , O.a. Reubem, A , A. Asaaga, S , F. Aondover, G . "Antibacterial Use and Level of Resistance in Poultry: A Retrospective Study in North-Central and South-West Nigeria". Journal of Poultry Research 15 (2018 ): 13-17
RIS	TY - JOUR T1 - Antibacterial Use and Level of Resistance in Poultry: A Retrospective Study in North-Central and South-West Nigeria AU - Kantiyok T. Josi̇ah , Arowolo O.a. Reubem , Semaka A. Asaaga , Gberindyer F. Aondover Y1 - 2018 PY - 2018 N1 - DO - T2 - Journal of Poultry Research JF - Journal JO - JOR SP - 13 EP - 17 VL - 15 IS - 1 SN - 1302-3209-2147-9003 M3 - UR - Y2 - 2020 ER -
EndNote	%0 Tavukçuluk Araştırma Dergisi Antibacterial Use and Level of Resistance in Poultry: A Retrospective Study in North-Central and South-West Nigeria %A Kantiyok T. Josi̇ah , Arowolo O.a. Reubem , Semaka A. Asaaga , Gberindyer F. Aondover %T Antibacterial Use and Level of Resistance in Poultry: A Retrospective Study in North-Central and South-West Nigeria %D 2018 %J Journal of Poultry Research %P 1302-3209-2147-9003 %V 15 %N 1 %R %U
ISNAD	T. Josi̇ah, Kantiyok , O.a. Reubem, Arowolo , A. Asaaga, Semaka , F. Aondover, Gberindyer . "Antibacterial Use and Level of Resistance in Poultry: A Retrospective Study in North-Central and South-West Nigeria". Journal of Poultry Research 15 / 1 (July 2018): 13-17 .
AMA	T. Josi̇ah K , O.a. Reubem A , A. Asaaga S , F. Aondover G . Antibacterial Use and Level of Resistance in Poultry: A Retrospective Study in North-Central and South-West Nigeria. JPS. 2018; 15(1): 13-17.
Vancouver	T. Josi̇ah K , O.a. Reubem A , A. Asaaga S , F. Aondover G . Antibacterial Use and Level of Resistance in Poultry: A Retrospective Study in North-Central and South-West Nigeria. Journal of Poultry Research. 2018; 15(1): 13-17.